Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.52 |
| ▸ | AVPR1B | P47901 | 8/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519206 | 0.84 | TAS1R3 (0.48) | TAS1R3TAS1R1MTTPPPARGTP53 | |
| SCHEMBL7751057 | 0.84 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1BMTTPPPARG | |
| SCHEMBL7374548 | 0.84 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL7336797 | 0.83 | AVPR2 (0.50) | AVPR2AVPR1AAVPR1BTP53 | |
| SCHEMBL7743965 | 0.82 | AVPR2 (0.52) | AVPR2AVPR1AAVPR1BMTTP | |
| Hydrochloric Acid SCHEMBL7368868 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL7749369 | 0.79 | AVPR2 (0.49) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL7512868 | 0.79 | TAS1R3 (0.56) | TAS1R3TAS1R1MTTPPPARGTP53 | |
| SCHEMBL7373974 | 0.78 | AVPR2 (0.47) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL7475780 | 0.78 | AVPR2 (0.49) | AVPR2AVPR1AAVPR1BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |