Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | MTTP | P55157 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519206 | 0.80 | TAS1R3 (0.48) | TAS1R3TAS1R1HPGDALDH1A1PPARG | |
| SCHEMBL8611075 | 0.79 | AVPR2 (0.52) | TAS1R3TAS1R1PPARGMTTPTP53 | |
| SCHEMBL7519406 | 0.79 | TAS1R3 (0.47) | TAS1R3TAS1R1ALDH1A1PPARGMTTP | |
| SCHEMBL8816771 | 0.77 | GAA (0.47) | HPGDALDH1A1KCNMA1NPSR1POLB | |
| SCHEMBL8816306 | 0.75 | MAPT (0.48) | TAS1R3TAS1R1HPGDALDH1A1TSHR | |
| SCHEMBL7512858 | 0.75 | ALDH1A1 (0.50) | HPGDALDH1A1KCNMA1MTTPTP53 | |
| SCHEMBL20860855 | 0.75 | TAS1R3 (0.79) | TAS1R3TAS1R1HPGDALDH1A1NPSR1 | |
| SCHEMBL7513974 | 0.74 | RAB9A (0.45) | HPGDALDH1A1PPARGKCNMA1NPSR1 | |
| SCHEMBL4202984 | 0.73 | TAS1R3 (1.00) | TAS1R3TAS1R1HPGDALDH1A1PPARG | |
| SCHEMBL7748399 | 0.72 | ALDH1A1 (0.51) | HPGDALDH1A1KCNMA1MTTPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |