Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856444 | 0.84 | ESR1 (0.52) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL29263288 | 0.84 | ESR1 (0.52) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL8613187 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL8861766 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TEAD4CARM1PRMT6 | |
| SCHEMBL2515877 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TEAD4CARM1PRMT6 | |
| SCHEMBL22966319 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL28882240 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TEAD4CARM1PRMT6 | |
| SCHEMBL3922244 | 0.77 | MAOA (0.53) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL3922242 | 0.77 | MAOA (0.53) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL2512315 | 0.76 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TEAD4CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821319-A | COMPRISING STRUCTURAL UNITS DERIVED FROM PYROMELLITIC ANHYDRIDE, TEREPHTHALOYL CHLORIDE, 1,3-BIS/4-(4-AMINOPHENOXY)-ALPHA,ALPHA-DIMETHYLBENZYL/BENZENE | MITSUI CHEMICALS, INC. (JP) | 1998-10-13 | — | — | US | disclosed |