Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749593 | 0.84 | LMNA (0.60) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8745657 | 0.84 | CHEK1 (0.74) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL25681987 | 0.82 | KMT2A (0.72) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3923314 | 0.81 | MEN1 (0.89) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10136190 | 0.80 | NPC1 (0.67) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11652739 | 0.79 | MEN1 (0.86) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12245070 | 0.79 | LMNA (0.67) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9697867 | 0.79 | L3MBTL1 (0.59) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21670265 | 0.77 | LMNA (0.66) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18882713 | 0.76 | MEN1 (0.72) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712322-A | Compositions of matter | ZENECA LIMITED (GB) | 1998-01-27 | — | — | US | disclosed |
| EP-0697025-B1 | COMPOSITIONS OF MATTER | ZENECA LTD (GB) | 1997-07-09 | — | — | EP | disclosed |
| EP-0697025-A1 | COMPOSITIONS OF MATTER | ZENECA LTD (GB) | 1996-02-21 | — | — | EP | disclosed |
| WO-1994024170-A1 | COMPOSITIONS OF MATTER | ZENECA LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |
| US-5283160-A | Containing a modified anthraquinone photoinitiator | ZENECA LIMITED (GB) | 1994-02-01 | — | — | US | disclosed |