SCHEMBL8745657

SCHEMBL8745657

CCCCC(CC)C(=O)Nc1ccc2c(c1)C(=O)NC2=O

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.74
ALDH1A1 P00352 4/20 0.63
KDM4E B2RXH2 3/20 0.63
HPGD P15428 2/20 0.63
ALOX12 P18054 1/20 0.63
GLA P06280 1/20 0.61
LMNA P02545 1/20 0.60
KMT2A Q03164 7/20 0.56
MEN1 O00255 6/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CASP3 P42574 2/20 0.51
POLB P06746 1/20 0.48
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8611242 0.84 ALDH1A1 (0.64) CHEK1ALDH1A1LMNAKMT2AMEN1
SCHEMBL8749593 0.82 LMNA (0.60) CHEK1ALDH1A1KDM4EHPGDALOX12
SCHEMBL25681987 0.78 KMT2A (0.72) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL12245070 0.78 LMNA (0.67) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL6260912 0.77 KDM4E (1.00) CHEK1ALDH1A1KDM4EHPGDALOX12
SCHEMBL22033208 0.76 KDM4E (0.92) CHEK1ALDH1A1KDM4EHPGDALOX12
SCHEMBL21670265 0.76 LMNA (0.66) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL18882713 0.76 MEN1 (0.72) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL11691670 0.76 MEN1 (0.72) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL9324598 0.76 MEN1 (0.72) ALDH1A1LMNAKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170164-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
US-H122-H PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-09-02 US claimed
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP claimed
WO-2012130780-A1 THIAZOLOPYRIMIDINE COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2012-10-04 WO disclosed
EP-0459349-B1 Silver halide color negative photosensitive material FUJI PHOTO FILM CO LTD (JP) 1997-03-26 EP disclosed
EP-0459458-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-02-12 EP disclosed
US-5518870-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-05-21 US disclosed
EP-0447921-B1 Silver halide colour photographic material FUJI PHOTO FILM CO LTD (JP) 1996-03-06 EP disclosed
EP-0324476-B1 Silver halide color photosensitive materials FUJI PHOTO FILM CO LTD (JP) 1995-06-21 EP disclosed
EP-0362808-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-05-10 EP disclosed
EP-0368340-B1 Method for processing silver halide color photosensitive materials FUJI PHOTO FILM CO LTD (JP) 1995-02-01 EP disclosed
US-H122-H PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-09-02 US disclosed
US-4594313-A Containing hetero rings FUJI PHOTO FILM CO., LTD. (JP) 1986-06-10 US disclosed
US-4590153-A CONTAINING MAGENTA COUPLER AND METAL COMPLEX FUJI PHOTO FILM CO., LTD. (JP) 1986-05-20 US disclosed
US-4585732-A MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1986-04-29 US disclosed
EP-0177765-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1986-04-16 EP disclosed
EP-0173256-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1986-03-05 EP disclosed
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP disclosed
US-4559297-A DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1985-12-17 US disclosed
EP-0164130-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-12-11 EP disclosed