Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8613933 | 0.99 | GRIN1 (0.39) | GRIN1GRIN2AGRIN2BSLC6A4HTR2A | |
| SCHEMBL8610623 | 0.89 | GRIN1 (0.47) | GRIN1GRIN2AGRIN2BSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8610065 | 0.84 | GRIN1 (0.39) | GRIN1GRIN2AGRIN2BSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8611332 | 0.84 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2BSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8614565 | 0.81 | S1PR1 (0.36) | GRIN1GRIN2AGRIN2BCACNA1GCACNA1H | |
| SCHEMBL7718906 | 0.74 | DRD2 (0.35) | GRIN1GRIN2AGRIN2BSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8615867 | 0.71 | SLC6A4 (0.37) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8694863 | 0.70 | SLC6A2 (0.36) | SLC6A4SLC6A2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL8706170 | 0.69 | DRD2 (0.34) | SLC6A2DRD2TACR1 | |
| Hydrochloric Acid SCHEMBL8706566 | 0.69 | DRD2 (0.33) | SLC6A2DRD2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773450-A | ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DISORDERS | PFIZER INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-5750535-A | Pharmaceutical agents for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria | PFIZER INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5744480-A | ANTIINFLAMMATORY AGENTS, NERVOUS SYSTEM DISORDERS | PFIZER INC. (US) | 1998-04-28 | — | — | US | disclosed |