SCHEMBL8611484

SCHEMBL8611484

CCC(C)(C)C1=CC=CC(=O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
MCL1 Q07820 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
CES2 O00748 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
CES1 P23141 1/20 0.31
MPI P34949 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5693515 0.79 ALDH1A1 (0.56) ATMALDH1A1MAPTMCL1CES2
SCHEMBL18637976 0.73 ACHE (0.32)
SCHEMBL1886441 0.69 ATM (0.34) ATMALDH1A1MAPTMCL1NPC1
SCHEMBL19490929 0.68
SCHEMBL8610511 0.68 ATM (0.53) ATMALDH1A1MAPTNPC1LMNA
SCHEMBL28307697 0.67 ATM (0.33) ATMALDH1A1MAPTNPC1LMNA
SCHEMBL8613270 0.67 ACHE (0.37) ATMALDH1A1MAPTNPC1LMNA
SCHEMBL8611923 0.67 ATM (0.38) ATMALDH1A1MAPTMCL1NPC1
SCHEMBL11775122 0.66
SCHEMBL11421705 0.66 ATM (0.36) ATMALDH1A1MAPTMCL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5780515-A APPLYING TO PLANTS; REDUCED TOXICITY AND IRRITATION ROCKHURST UNIVERSITY (US) 1998-07-14 US claimed