Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30992110 | 0.83 | CA1 (0.50) | TP53CA1CA2TSHRALDH1A1 | |
| SCHEMBL476857 | 0.83 | CA1 (0.50) | TP53CA1CA2TSHRALDH1A1 | |
| SCHEMBL30422061 | 0.82 | ALDH1A1 (0.46) | CA2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL2322069 | 0.82 | ALDH1A1 (0.46) | CA2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL8459532 | 0.82 | CA1 (0.48) | TP53CA1CA2TSHRALDH1A1 | |
| SCHEMBL14604217 | 0.81 | DRD2 (0.40) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6395598 | 0.80 | APP (0.44) | TP53CA1CA2ALDH1A1HPGD | |
| SCHEMBL56425 | 0.80 | CA1 (0.50) | TP53CA1CA2TSHRALDH1A1 | |
| SCHEMBL15656939 | 0.80 | CA1 (0.50) | TP53CA1CA2TSHRMAPT | |
| Dimethylamine SCHEMBL8610644 | 0.79 | HSD17B10 (0.41) | MAPTALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |