Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422061 | 0.93 | ALDH1A1 (0.46) | HSD17B10ALDH1A1HPGDBCL2L1ESR2 | |
| SCHEMBL2322069 | 0.93 | ALDH1A1 (0.46) | HSD17B10ALDH1A1HPGDBCL2L1ESR2 | |
| SCHEMBL1120987 | 0.80 | CYP3A4 (0.58) | ESR2ESR1TDP1CYP3A4DRD1 | |
| SCHEMBL19674305 | 0.80 | MAPT (0.39) | HSD17B10ALDH1A1HPGDESR2ESR1 | |
| SCHEMBL8611732 | 0.79 | TP53 (0.46) | HSD17B10ALDH1A1HPGDBCL2L1ESR2 | |
| SCHEMBL8610643 | 0.78 | RAB9A (0.43) | HSD17B10ALDH1A1HPGDBCL2L1TDP1 | |
| SCHEMBL31059891 | 0.78 | CYP3A4 (0.55) | ESR2ESR1TDP1CYP3A4DRD1 | |
| Water SCHEMBL1131752 | 0.78 | CYP3A4 (0.55) | ESR2ESR1TDP1CYP3A4DRD1 | |
| Water SCHEMBL1131329 | 0.78 | CYP3A4 (0.55) | ESR2ESR1TDP1CYP3A4DRD1 | |
| Bromide SCHEMBL8660152 | 0.78 | CYP3A4 (0.55) | ESR2ESR1TDP1CYP3A4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |