Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611672 | 0.74 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL6956052 | 0.73 | STS (0.44) | — | |
| SCHEMBL6956048 | 0.72 | STS (0.45) | TSHRMAPTALDH1A1LMNA | |
| SCHEMBL29407510 | 0.71 | TSHR (0.65) | KMT2ATSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL3378134 | 0.71 | TSHR (0.65) | KMT2ATSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL5534601 | 0.71 | STS (0.40) | — | |
| SCHEMBL28499155 | 0.70 | MTNR1A (0.61) | MTNR1AMTNR1BKMT2ATSHRMAPT | |
| SCHEMBL8928239 | 0.69 | KMT2A (0.65) | KMT2ATSHRMAPTALDH1A1GAA | |
| SCHEMBL28922787 | 0.69 | STS (0.45) | — | |
| SCHEMBL10114184 | 0.68 | KMT2A (0.52) | KMT2ATSHRMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |