Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 9/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 9/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 9/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 9/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.53 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.53 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.53 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612108 | 0.81 | GRIK1 (0.50) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8607444 | 0.81 | MAPT (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8612845 | 0.81 | OPRM1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610303 | 0.81 | GRIK1 (0.41) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL3343914 | 0.80 | MEN1 (0.57) | LMNACYP1A2MAPTHPGD | |
| SCHEMBL8072110 | 0.79 | ALDH1A1 (0.44) | LMNACYP1A2CYP3A4MAPTHPGD | |
| SCHEMBL28999954 | 0.79 | MAPT (0.46) | LMNACYP1A2CYP3A4MAPTHPGD | |
| SCHEMBL29271622 | 0.79 | SMN1; SMN2 (0.46) | LMNACYP1A2MAPTHPGD | |
| SCHEMBL30803845 | 0.79 | VCAM1 (0.48) | LMNACYP1A2MAPTHPGD | |
| SCHEMBL3341502 | 0.79 | VCAM1 (0.48) | LMNACYP1A2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |