Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010387 | 0.77 | THRB (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL28413946 | 0.77 | THRB (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9895429 | 0.76 | THRB (0.38) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL7205636 | 0.76 | CA12 (0.33) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL28613268 | 0.73 | CA12 (0.37) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL11234258 | 0.71 | TSHR (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL31473039 | 0.71 | THRB (0.40) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL28600061 | 0.71 | THRB (0.40) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL8837210 | 0.71 | THRB (0.40) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL28198689 | 0.71 | ADRB2 (0.39) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817302-A | POLYSILSESQUISILOXANES, COSMETICS | GENERAL ELECTRIC COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5684112-A | Low viscosity organofunctionalized siloxysilicates and cosmetic formulations therewith | GENERAL ELECTRIC COMPANY (US) | 1997-11-04 | — | — | US | disclosed |