Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616550 | 1.00 | GPR34 (0.63) | GPR34FFAR1MAOBGSTP1NR4A2 | |
| SCHEMBL8616528 | 0.90 | GPR34 (0.55) | GPR34FFAR1MAOBGSTP1NR4A2 | |
| SCHEMBL8612458 | 0.89 | GSTP1 (0.55) | GPR34FFAR1MAOBGSTP1NR4A2 | |
| SCHEMBL26830356 | 0.89 | MAOB (0.58) | GPR34FFAR1MAOBNR4A2FFAR4 | |
| SCHEMBL8612150 | 0.87 | GPR34 (0.53) | GPR34FFAR1MAOBGSTP1NR4A2 | |
| SCHEMBL8616159 | 0.87 | GSTP1 (0.56) | GPR34FFAR1MAOBGSTP1NR4A2 | |
| SCHEMBL8614234 | 0.86 | GPR34 (0.51) | GPR34FFAR1MAOBGSTP1NR4A2 | |
| SCHEMBL16346074 | 0.85 | GSTP1 (0.66) | FFAR1MAOBGSTP1NR4A2MCL1 | |
| SCHEMBL23483029 | 0.84 | LMNA (0.69) | FFAR1MAOBGSTP1NR4A2MCL1 | |
| SCHEMBL1096817 | 0.84 | LMNA (0.69) | FFAR1MAOBGSTP1NR4A2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |