SCHEMBL861248

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL861249	1.00	CLK4 (0.44)	CLK4DYRK1BTYRO3NTRK2HRH3
	SCHEMBL860443	0.91	CLK4 (0.50)	CLK4DYRK1BTYRO3NTRK2PARP10
	SCHEMBL860444	0.91	CLK4 (0.50)	CLK4DYRK1BTYRO3NTRK2PARP10
	SCHEMBL860649	0.90	CLK4 (0.38)	CLK4DYRK1BTYRO3NTRK2HRH3
	SCHEMBL860648	0.90	CLK4 (0.38)	CLK4DYRK1BTYRO3NTRK2HRH3
	SCHEMBL861046	0.90	PARP10 (0.44)	CLK4DYRK1BHRH3PARP10PARP11
	SCHEMBL861212	0.90	GSTP1 (0.35)	CLK4DYRK1BTYRO3NTRK2HRH3
	SCHEMBL2598039	0.90	GSTP1 (0.35)	CLK4DYRK1BTYRO3NTRK2HRH3
	SCHEMBL861211	0.90	GSTP1 (0.35)	CLK4DYRK1BTYRO3NTRK2HRH3
	SCHEMBL861047	0.90	PARP10 (0.44)	CLK4DYRK1BHRH3PARP10PARP11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.