Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | FBP1 | P09467 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130064 | 1.00 | APP (0.60) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL4750994 | 0.82 | APP (0.62) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL461047 | 0.82 | APP (0.62) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL9170800 | 0.81 | APP (0.78) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL14947048 | 0.81 | APP (0.78) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL458178 | 0.81 | APP (0.78) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL458177 | 0.81 | APP (0.78) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL9170804 | 0.81 | APP (0.78) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL10836804 | 0.81 | APP (0.60) | APPFBP1MAPTNPC1RAB9A | |
| SCHEMBL10836802 | 0.81 | APP (0.60) | APPFBP1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822933-B1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | COUNCIL SCIENT IND RES (IN) | 2016-12-28 | — | — | EP | disclosed |
| US-9096498-B2 | CuCN-mediated one pot production of cinnamonitrile derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-08-04 | — | — | US | disclosed |
| US-9096498-B2 | CuCN-mediated one pot production of cinnamonitrile derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-08-04 | — | — | US | disclosed |
| US-20150031899-A1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-29 | — | — | US | disclosed |
| US-20150031899-A1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-29 | — | — | US | disclosed |
| WO-2008127139-A1 | INDICYANINE DYES AND THE DERIVATIVES THEREOF FOR ANALYSING BIOLOGICAL MICROMOLECULES | INSTITUT MOLEKULYARNOI BIOLOGII IM. V.A. ENGELDARDTA ROSSIISKOI AKADEMII NAUK (RU) | 2008-10-23 | — | — | WO | disclosed |
| US-5721240-A | PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5565463-A | PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0460116-A4 | 9-SUBSTITUTED-8-UNSUBSTITUTED-9-DEAZAGUANINES | — | 1992-05-13 | — | — | EP | disclosed |
| EP-0460116-A1 | 9-SUBSTITUTED-8-UNSUBSTITUTED-9-DEAZAGUANINES. | BIOCRYST (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990010631-A1 | 9-SUBSTITUTED-8-UNSUBSTITUTED-9-DEAZAGUANINES | BIOCRYST (US) | 1990-09-20 | — | — | WO | disclosed |
| US-4564479-A | PALLADIUM COMPOUND, PHOSPHORUS OR ARSENIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1986-01-14 | — | — | US | disclosed |
| US-4101543-A | DYES FOR CELLULOSE ACETATES, AROMATIC POLYESTERS OR POLYAMIDES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-07-18 | — | — | US | disclosed |
| US-4012377-A | ANTIMICROBIAL, PARASITICIDES | GLAXO LABORATORIES LIMITED (EN) | 1977-03-15 | — | — | US | disclosed |
| US-4010151-A | Water insoluble mono azo and disazo dyes containing cinnamonitrile group | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-03-01 | — | — | US | disclosed |
| US-4008213-A | WATER INSOLUBLE | UGINE KUHLMANN (FR) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031899-A1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | NISCH, PNN, NCLN | APP 2989/4885FBP1 2729/4885MAPT 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.