SCHEMBL8612600

SCHEMBL8612600

CC1OC1(C)Cc1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.46
PKM P14618 1/20 0.40
TSHR P16473 1/20 0.40
CHRM2 P08172 3/20 0.39
CHRM5 P08912 3/20 0.39
CHRM3 P20309 2/20 0.39
LOX P28300 1/20 0.39
CHRM1 P11229 2/20 0.39
CHRM4 P08173 1/20 0.39
NAMPT P43490 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
POLB P06746 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP26B1 Q9NR63 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615501 0.79 HTR6 (0.47) HTR6PKMTSHRCHRM2CHRM5
Hydrochloric Acid SCHEMBL29078695 0.78 MAOA (0.41) L3MBTL1
SCHEMBL8611763 0.75 HTR6 (0.46) HTR6PKMTSHRCHRM2CHRM5
SCHEMBL8846929 0.73 HTR6 (0.41) HTR6PKMTSHRCHRM2CHRM5
SCHEMBL8846820 0.73 HTR6 (0.41) HTR6PKMTSHRCHRM2CHRM5
SCHEMBL6297171 0.71 HTR6 (0.49) HTR6PKMTSHRCHRM2CHRM5
SCHEMBL8611324 0.71 HTR6 (0.53) HTR6PKMTSHRLOXNAMPT
SCHEMBL9857208 0.71 TSHR (0.41) TSHRCHRM2CHRM5CHRM3CHRM1
SCHEMBL4615611 0.70 HTR6 (0.61) HTR6L3MBTL1HTR2AHTR2CPOLB
SCHEMBL8613488 0.70 HTR6 (0.41) HTR6PKMTSHRCHRM2CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0664224-B1 Heat-sensitive recording paper NEW OJI PAPER CO LTD (JP) 1998-04-22 EP disclosed
US-5543382-A GLASSINE PAPER, LEUCO DYE AND DEVELOPER NEW OJI PAPER CO., LTD. (JP) 1996-08-06 US disclosed
EP-0664224-A2 Heat-sensitive recording paper NEW OJI PAPER CO., LTD. (JP) 1995-07-26 EP disclosed