SCHEMBL8613488

SCHEMBL8613488

CCCCC1(Cc2ccc(S(=O)(=O)c3ccccc3)cc2)CO1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.41
ABCB1 P08183 6/20 0.38
ABCC1 P33527 4/20 0.38
CCR5 P51681 2/20 0.38
LOX P28300 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CHRM2 P08172 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM3 P20309 1/20 0.36
PKM P14618 1/20 0.35
TSHR P16473 1/20 0.35
MAOA P21397 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8611763 0.87 HTR6 (0.46) HTR6LOXSMN1; SMN2L3MBTL1CHRM2
SCHEMBL8615501 0.77 HTR6 (0.47) HTR6LOXSMN1; SMN2L3MBTL1CHRM2
SCHEMBL10180568 0.73 CA2 (0.62) HTR6TDP1LMNAHTTSMN1; SMN2
SCHEMBL8611324 0.71 HTR6 (0.53) HTR6LOXSMN1; SMN2L3MBTL1PKM
SCHEMBL28954365 0.70 CA2 (0.62) HTR6LMNASMN1; SMN2CHRM2CHRM5
SCHEMBL8612600 0.70 HTR6 (0.46) HTR6LOXSMN1; SMN2L3MBTL1CHRM2
SCHEMBL4618112 0.69 HTR6 (0.67) HTR6MEN1LMNAHTTKMT2A
SCHEMBL4615611 0.69 HTR6 (0.61) HTR6LMNASMN1; SMN2L3MBTL1
SCHEMBL14778575 0.67 MMP2 (0.42) MEN1LMNAHTTKMT2ASMN1; SMN2
SCHEMBL28009906 0.67 CA1 (0.38) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0664224-B1 Heat-sensitive recording paper NEW OJI PAPER CO LTD (JP) 1998-04-22 EP disclosed
US-5543382-A GLASSINE PAPER, LEUCO DYE AND DEVELOPER NEW OJI PAPER CO., LTD. (JP) 1996-08-06 US disclosed
EP-0664224-A2 Heat-sensitive recording paper NEW OJI PAPER CO., LTD. (JP) 1995-07-26 EP disclosed