SCHEMBL8612751

SCHEMBL8612751

CC(C)Oc1ccc(S(=O)(=O)c2ccc(OC(=O)OCc3ccccc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.61
NAMPT P43490 2/20 0.48
CTRC Q99895 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
CNR2 P34972 3/20 0.46
LMNA P02545 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
HTT P42858 1/20 0.43
GFER P55789 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
PTGDR Q13258 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26381709 0.86 PKM (0.53) LMNAMEN1KMT2AALDH1A1GAA
SCHEMBL8613949 0.83 GAA (0.51) HTR2ANAMPTLMNAL3MBTL1KMT2A
SCHEMBL8614581 0.83 HTR2A (0.51) HTR2ANAMPTNPC1RAB9ALMNA
SCHEMBL8581163 0.81 CTRC (0.60) CTRCNPC1RAB9ACNR2LMNA
SCHEMBL8612386 0.80 HTR2A (0.48) HTR2ANAMPTNPC1RAB9ALMNA
SCHEMBL7669154 0.79 KMT2A (0.49) HTR2ALMNAL3MBTL1MEN1KMT2A
SCHEMBL7673657 0.79 HSD17B10 (0.52) HTR2ALMNAL3MBTL1MEN1KMT2A
SCHEMBL7669158 0.79 KMT2A (0.49) HTR2ALMNAL3MBTL1MEN1KMT2A
SCHEMBL8611733 0.79 HTR2A (0.47) HTR2ANAMPTNPC1RAB9ALMNA
SCHEMBL4613497 0.78 HTR6 (0.54) NAMPTCNR2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605149-B1 Recording sheet JUJO PAPER CO LTD (JP) 1998-04-22 EP disclosed
US-5482913-A CARBONATE TYPE BLOCKED COLOR DEVELOPER, LASER RECORDING NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 1996-01-09 US disclosed
EP-0605149-A2 Recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1994-07-06 EP disclosed