Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612805 | 0.74 | MCHR1 (0.32) | MCHR1MEN1ALDH1A1LMNAMAPT | |
| Biphenyl SCHEMBL312988 | 0.60 | HTT (0.59) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL16361074 | 0.59 | HTT (0.57) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL2058591 | 0.59 | HTT (0.57) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL537243 | 0.59 | HTT (0.57) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL425356 | 0.56 | HTT (0.69) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL17081753 | 0.56 | HTT (0.69) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL12355 | 0.56 | HTT (0.69) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL3874015 | 0.56 | TEAD4 (0.59) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL1096473 | 0.56 | NCOA1 (0.68) | PTGS2MEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | disclosed |