SCHEMBL8613058

SCHEMBL8613058

OCC(O)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618904 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL8613261 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL8618882 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL197103 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL8615806 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL8614285 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL197970 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL8615800 1.00 ALDH1A1 (0.35) ALDH1A1LMNATHRB
SCHEMBL5353296 0.98 LMNA (0.36) ALDH1A1LMNATHRB
SCHEMBL7774883 0.93 LMNA (0.40) ALDH1A1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220118379-A1 Separation of Radiometals TECHNICAL UNIVERSITY OF DENMARK (DK) 2022-04-21 US disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed
US-5254660-A Polyurethanes, fluoropolymers BAYER AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
EP-0540976-A1 Use of polyisocyanate solutions for the impregnation of mineral substrates BAYER AG (DE) 1993-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220118379-A1 Separation of Radiometals SLC39A3, SLC30A6, SLC39A14 ALDH1A1 4561/4885LMNA 1932/4885THRB 3837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.