Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613059 | 0.93 | PLG (0.34) | EPHX1ALDH1A1LMNA | |
| SCHEMBL28995556 | 0.79 | EPHX1 (0.45) | EPHX1ALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL28995554 | 0.79 | EPHX1 (0.45) | EPHX1ALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL9607899 | 0.75 | SHBG (0.35) | EPHX1ALDH1A1 | |
| SCHEMBL12152925 | 0.75 | EPHX1 (0.35) | EPHX1ALDH1A1 | |
| SCHEMBL14463106 | 0.75 | SMN1; SMN2 (0.42) | EPHX1ALDH1A1CES2CES1POLB | |
| SCHEMBL11859113 | 0.74 | EPHX1 (0.36) | EPHX1ALDH1A1 | |
| SCHEMBL14451346 | 0.74 | SHBG (0.33) | EPHX1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7189500 | 0.73 | CES2 (0.39) | EPHX1ALDH1A1CES2CES1POLB | |
| SCHEMBL26186177 | 0.73 | ADRB2 (0.37) | EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656334-B1 | Process for the production of cyclohexanedimethanol, with preponderance of the trans-isomer | EASTMAN CHEM CO (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0656338-B1 | Vapour phase hydrogenation of esters or lactones to hydroxy compounds | EASTMAN CHEM CO (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0656337-B1 | Process for the production of 1,4-cyclohexanedimethanol | EASTMAN CHEM CO (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0656337-A1 | Process for the production of 1,4-cydohexanedimethanol | EASTMAN CHEMICAL COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0656334-A1 | Process for the production of cydohexanedimethanol, with preponderance of the trans-isomer | EASTMAN CHEMICAL COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0656338-A1 | Vapour phase hydrogenation of esters or lactones to hydroxy compounds | EASTMAN CHEMICAL COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| US-5395987-A | Hydrogenation of ester | EASTMAN CHEMICAL COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| US-5395986-A | Hydrogenation of dialkyl cyclohexanedicarboxylate using copper or group VIII compound catalysts; high trans configuration to cis ratio | EASTMAN CHEMICAL COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| US-5395991-A | Regeneration of hydrogenation catalyst | EASTMAN CHEMICAL COMPANY (US) | 1995-03-07 | — | — | US | disclosed |