SCHEMBL8613076

SCHEMBL8613076

CCC(C)(C)c1cc(O)cc(O)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 2/20 0.38
TYR P14679 2/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
CYP2C9 P11712 1/20 0.38
MIF P14174 1/20 0.38
HTT P42858 1/20 0.38
NFE2L2 Q16236 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PTGS1 P23219 1/20 0.36
DRD3 P35462 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
MAPT P10636 1/20 0.34
ATP2A2 P16615 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188294 0.89 CA2 (0.41) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL8377448 0.82 SMN1; SMN2 (0.38) ALDH1A1ALOX15LMNACYP2C9HTT
SCHEMBL8611108 0.78 CA2 (0.54) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL15294394 0.76 CYP3A4 (0.40) ALDH1A1ALOX15TYRCYP3A4MEN1
SCHEMBL30026979 0.75 ALDH1A1 (0.63) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL3435872 0.75 TYR (0.47) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL133971 0.75 ALDH1A1 (0.63) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL34690 0.75 ALDH1A1 (0.55) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL1160345 0.74 SMN1; SMN2 (0.41) ALDH1A1ALOX15TYRLMNACYP2C9
SCHEMBL55598 0.74 ALDH1A1 (0.60) ALDH1A1ALOX15TYRLMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5780515-A APPLYING TO PLANTS; REDUCED TOXICITY AND IRRITATION ROCKHURST UNIVERSITY (US) 1998-07-14 US claimed