Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21195871 | 0.72 | TLR8 (0.46) | GAAKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8642261 | 0.67 | PTGES (0.37) | GAAHTTKMT2AGLP1RKDM4E | |
| SCHEMBL2885675 | 0.66 | NQO1 (0.34) | KMT2AKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10896589 | 0.66 | KDM4E (0.34) | HTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8828083 | 0.65 | MMP1 (0.42) | GAAKMT2AGLP1RKDM4EALDH1A1 | |
| SCHEMBL11395208 | 0.62 | GLP1R (0.45) | GAAHTTKMT2AGLP1RPGK1 | |
| SCHEMBL29185057 | 0.61 | MAT2A (0.41) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL693644 | 0.61 | PDGFRB (0.35) | — | |
| SCHEMBL24271589 | 0.60 | KDM4E (0.57) | GAAHTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2892944 | 0.60 | KDM4E (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640612-B1 | Novel derivatives from 2-(1H)-quinolinone, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-04-22 | — | — | EP | disclosed |
| EP-0640612-A1 | Novel derivatives from 2-(1H)-quinolinone, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-03-01 | — | — | EP | disclosed |