SCHEMBL861337

SCHEMBL861337

Cc1ccc2c(c1)c1ccccc1c1nc(CC(C)(C)C)cn21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.40
RORA P35398 2/20 0.40
RORC P51449 2/20 0.40
RORB Q92753 2/20 0.40
MEN1 O00255 1/20 0.37
NR1I2 O75469 1/20 0.37
AHR P35869 1/20 0.37
KMT2A Q03164 1/20 0.37
CCR4 P51679 1/20 0.33
MAPT P10636 4/20 0.32
LMNA P02545 4/20 0.32
TSHR P16473 3/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 2/20 0.32
HPGD P15428 1/20 0.32
CREBBP Q92793 1/20 0.32
NLRP3 Q96P20 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.31
PDE5A O76074 1/20 0.31
PDE1B Q01064 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861778 0.77 PTAFR (0.38) PGRRORARORCRORBMEN1
SCHEMBL12759585 0.74 RORA (0.32) PGRRORARORCRORB
SCHEMBL31484378 0.73 MEN1 (0.38) PGRRORARORCRORBMEN1
SCHEMBL23922311 0.70 MEN1 (0.38) PGRRORARORCRORBMEN1
SCHEMBL12759590 0.70 MAPT (0.39) PGRRORARORCRORBMEN1
SCHEMBL20313295 0.70 MEN1 (0.39) PGRRORARORCRORBMEN1
SCHEMBL841596 0.68 IKBKB (0.46) PGRRORARORCRORBMEN1
SCHEMBL29929754 0.65 ADORA2A (0.35) MEN1KMT2AMAPTLMNATSHR
SCHEMBL861330 0.65 HSD17B10 (0.47) MAPTLMNATSHRALDH1A1POLB
SCHEMBL13350160 0.64 MEN1 (0.46) PGRRORARORCRORBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C PGR 3621/4885RORA 2304/4885RORC 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.