SCHEMBL861330

SCHEMBL861330

Cc1cn2c3ccccc3c3ccccc3c2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.47
ALDH1A1 P00352 5/20 0.47
HPGD P15428 4/20 0.47
KDM4E B2RXH2 6/20 0.40
LMNA P02545 3/20 0.40
MAPT P10636 3/20 0.40
TSHR P16473 3/20 0.40
POLB P06746 2/20 0.40
GPR3 P46089 2/20 0.39
ADORA2A P29274 4/20 0.38
ADORA3 P0DMS8 2/20 0.38
ADORA1 P30542 2/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CDK4 P11802 1/20 0.36
CCND3 P30281 1/20 0.36
PTAFR P25105 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20313295 0.87 MEN1 (0.39) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL16728807 0.82 ALKBH5 (0.40) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL15772139 0.80 ALDH1A1 (0.41) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL15788578 0.78 MAPT (0.36) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL16328883 0.78 KDM4E (0.35) HSD17B10ALDH1A1KDM4ELMNAMAPT
SCHEMBL12759590 0.77 MAPT (0.39) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL12759589 0.77 DDB1 (0.41) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL12759587 0.77 MAPT (0.37) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL21334235 0.77 HSD17B10 (0.38) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL861778 0.77 PTAFR (0.38) HSD17B10ALDH1A1HPGDKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-10017691-B2 Organic electroluminescent element, display device and lighting device Konica Minolta, Inc. (JP) 2018-07-10 US disclosed
US-20150318499-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE MERCK PATENT GMBH (DE) 2015-11-05 US disclosed
US-9126943-B2 Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-08 US disclosed
US-9126943-B2 Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-08 US disclosed
US-20120132899-A1 NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-31 US disclosed
US-20120132899-A1 NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-31 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-20100141126-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-06-10 US disclosed
US-20100141125-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-06-10 US disclosed
US-20100141125-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-06-10 US disclosed
US-20100141125-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-06-10 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10017691-B2 Organic electroluminescent element, display device and lighting device L1CAM, ELOVL1, LAGE3 HSD17B10 2065/4885ALDH1A1 350/4885HPGD 2037/4885
US-20120132899-A1 NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME H1-2, L1CAM, H1-0 HSD17B10 1952/4885ALDH1A1 191/4885HPGD 2787/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 HSD17B10 2728/4885ALDH1A1 983/4885HPGD 1487/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C HSD17B10 4802/4885ALDH1A1 1365/4885HPGD 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.