Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963182 | 0.80 | DRD2 (0.52) | ROCK1POLBDRD2DRD3EHMT2 | |
| SCHEMBL11498081 | 0.77 | EPHX1 (0.56) | ROCK1KMT2AEPHX1POLBROCK2 | |
| SCHEMBL1726902 | 0.77 | EPHX1 (0.56) | ROCK1KMT2AEPHX1POLBROCK2 | |
| SCHEMBL25451316 | 0.77 | EPHX1 (0.56) | ROCK1KMT2AEPHX1POLBROCK2 | |
| SCHEMBL8613430 | 0.76 | KDM4E (0.50) | ROCK1KMT2AEPHX1POLBS1PR1 | |
| Water SCHEMBL11247605 | 0.76 | EPHX1 (0.54) | ROCK1KMT2AEPHX1POLBROCK2 | |
| SCHEMBL11169098 | 0.75 | EPHX1 (0.49) | ROCK1KMT2AEPHX1POLBROCK2 | |
| SCHEMBL11175342 | 0.75 | EPHX1 (0.53) | ROCK1KMT2AEPHX1POLBROCK2 | |
| SCHEMBL10372739 | 0.75 | CTSD (0.48) | ROCK1KMT2AEPHX1POLBDRD2 | |
| SCHEMBL14980372 | 0.75 | POLB (0.64) | ROCK1POLBDRD2DRD3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |