Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.55 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613361 | 0.96 | KDM4E (0.52) | KDM4ELMNAHTTPTGER4PLAUR | |
| SCHEMBL8615990 | 0.87 | CCR6 (0.57) | KDM4ELMNAHTTPTGER4POLB | |
| SCHEMBL8616695 | 0.87 | MEN1 (0.46) | KDM4ELMNAPTGER4ALDH1A1MEN1 | |
| SCHEMBL8618761 | 0.86 | MEN1 (0.56) | KDM4ELMNAPTGER4POLBALDH1A1 | |
| SCHEMBL8619899 | 0.86 | MEN1 (0.46) | KDM4ELMNAPTGER4ALDH1A1MEN1 | |
| SCHEMBL8617709 | 0.85 | PDE10A (0.69) | KDM4EHTTPOLBALDH1A1MEN1 | |
| SCHEMBL8618914 | 0.85 | CYP2C9 (0.46) | LMNAPTGER4ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8619359 | 0.84 | CYP2C9 (0.46) | LMNAPTGER4ALDH1A1MEN1KMT2A | |
| SCHEMBL8618987 | 0.84 | KMT2A (0.51) | KDM4EPTGER4POLBALDH1A1MEN1 | |
| SCHEMBL8620105 | 0.84 | PDE10A (0.45) | KDM4EPTGER4POLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |