Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988118 | 0.78 | TACR1 (0.51) | CKS1BSKP1SKP2TACR1 | |
| SCHEMBL11987483 | 0.67 | ATR (0.62) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL5927363 | 0.64 | HDAC1 (0.41) | CKS1BSKP1SKP2S1PR1 | |
| SCHEMBL31248609 | 0.64 | GRM2 (0.51) | MEN1KMT2ANPSR1AAK1MAPT | |
| SCHEMBL5927008 | 0.63 | S1PR1 (0.39) | CKS1BSKP1SKP2S1PR1CTSS | |
| SCHEMBL31580479 | 0.63 | CPB2 (0.38) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL28256776 | 0.63 | NQO2 (0.54) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL20014854 | 0.62 | MTNR1A (0.61) | MEN1KMT2AMALT1IDO1CTSS | |
| SCHEMBL28003948 | 0.62 | SMN1; SMN2 (0.43) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL15283620 | 0.62 | CKS1B (0.50) | CKS1BSKP1SKP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786352-A | CARDIOVASCULAR DISORDERS, TACHYKININ RECEPTOR ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |