Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224497 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2TACR1ALDH1A1CYP2C9KDM4E | |
| SCHEMBL6772451 | 0.75 | LMNA (0.42) | SMN1; SMN2TACR1ALDH1A1TDP1LMNA | |
| SCHEMBL9870996 | 0.73 | KDM4E (0.58) | SMN1; SMN2TACR1JMJD6TP53ALDH1A1 | |
| SCHEMBL28143127 | 0.72 | CDC7 (0.46) | SMN1; SMN2CYP3A4GAALMNAMEN1 | |
| SCHEMBL31091354 | 0.72 | ADORA3 (0.57) | SMN1; SMN2JMJD6TP53ALDH1A1CYP1A2 | |
| SCHEMBL6986301 | 0.72 | ALDH1A1 (0.54) | SMN1; SMN2JMJD6TP53ALDH1A1CYP1A2 | |
| SCHEMBL28007800 | 0.72 | HDAC7 (0.48) | SMN1; SMN2TP53ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL23791802 | 0.71 | RAB9A (0.56) | SMN1; SMN2TP53ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2223945 | 0.71 | PDCD1 (0.48) | SMN1; SMN2TP53ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15166672 | 0.69 | ADORA3 (0.56) | SMN1; SMN2TP53ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557691-B | A kind of 3 amine acyl bishydrazide derivatives and its preparation method and application | 中国农业大学 | 2017-10-24 | — | — | CN | disclosed |
| CN-104610140-B | 3-amine acylhydrazone derivative, preparation method and application of 3-amine acylhydrazone derivative | 青岛农业大学 | 2017-01-25 | — | — | CN | disclosed |
| CN-104610140-A | 3-amine acylhydrazone derivative, preparation method and application of 3-amine acylhydrazone derivative | UNIV QINGDAO AGRICULTURAL | 2015-05-13 | — | — | CN | disclosed |
| CN-104557691-A | 3-aminoacyl bishydrazide derivatives, and preparation method and application thereof | UNIV CHINA AGRICULTURAL | 2015-04-29 | — | — | CN | disclosed |