Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.62 |
| ▸ | NQO2 | P16083 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611942 | 0.83 | HPGDS (0.58) | HPGDSNQO2KMT2ARAB9AMAPT | |
| SCHEMBL434888 | 0.82 | HPGDS (0.62) | HPGDSNQO2KMT2ARAB9AMAPT | |
| SCHEMBL29923835 | 0.82 | MAPT (0.45) | HPGDSKMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10320559 | 0.81 | PARP1 (0.45) | HPGDSKMT2ARAB9AMAPTMEN1 | |
| SCHEMBL15703131 | 0.81 | PSMD14 (0.62) | HPGDSRAB9ANPC1RELAPARP1 | |
| SCHEMBL23858507 | 0.81 | HPGDS (0.60) | HPGDSNQO2KMT2ARAB9AMAPT | |
| SCHEMBL2134025 | 0.81 | HPGDS (0.60) | HPGDSNQO2KMT2ARAB9AMAPT | |
| SCHEMBL8611935 | 0.81 | HPGDS (0.60) | HPGDSNQO2KMT2ARAB9AMAPT | |
| SCHEMBL15034698 | 0.81 | HPGDS (0.60) | HPGDSNQO2KMT2ARAB9AMAPT | |
| SCHEMBL13255497 | 0.81 | HPGDS (0.60) | HPGDSNQO2KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824689-A | 3,8-DIHYROXYQUINOLINE AND DERIVATIVES, ANTICANCER AGENT, PREPARATION FROM 8-ALKOXYQUINOLINE-3-CARBOXAMIDE, HOFFMAN REARRANGEMENT, DIAZOTIZATION | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 1998-10-20 | — | — | US | claimed |
| US-5824689-A | 3,8-DIHYROXYQUINOLINE AND DERIVATIVES, ANTICANCER AGENT, PREPARATION FROM 8-ALKOXYQUINOLINE-3-CARBOXAMIDE, HOFFMAN REARRANGEMENT, DIAZOTIZATION | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 1998-10-20 | — | — | US | disclosed |