Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Jineol Methyl Ether SCHEMBL8613544 | 0.82 | HPGDS (0.62) | MAPTKDM4EHPGDSRELAPARP1 | |
| SCHEMBL28294415 | 0.81 | SLC40A1 (0.44) | PIK3CDHPGDSRELAPARP1CYP1A2 | |
| SCHEMBL15703131 | 0.81 | PSMD14 (0.62) | KDM4EHPGDSRELAPARP1CYP1A2 | |
| SCHEMBL10320559 | 0.81 | PARP1 (0.45) | MAPTKDM4EHPGDSRELAPARP1 | |
| SCHEMBL30492638 | 0.81 | RELA (0.52) | RELACYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL6347577 | 0.81 | RELA (0.52) | RELACYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL1408873 | 0.77 | CYP1A2 (0.50) | MAPTL3MBTL1RELACYP1A2CYP2A6 | |
| SCHEMBL30492598 | 0.77 | CCR1 (0.62) | MAPTKDM4EL3MBTL1RELACYP1A2 | |
| SCHEMBL6356302 | 0.77 | CCR1 (0.62) | MAPTKDM4EL3MBTL1RELACYP1A2 | |
| SCHEMBL7376462 | 0.77 | PSMD14 (0.67) | KDM4EPARP1CYP1A2CYP2A6PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |