Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.86 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612623 | 0.79 | LMNA (0.69) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22204443 | 0.78 | MEN1 (0.68) | KMT2AMEN1LMNACA12CA9 | |
| SCHEMBL5604160 | 0.77 | ESR1 (0.73) | KMT2AMEN1ALDH1A1CA12CA9 | |
| SCHEMBL4335752 | 0.76 | KMT2A (0.62) | KMT2AMEN1LMNAALDH1A1CA12 | |
| SCHEMBL1618178 | 0.76 | LMNA (0.73) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL2966811 | 0.76 | LMNA (0.73) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22204394 | 0.75 | MEN1 (0.65) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8224221 | 0.75 | ESR1 (0.75) | KMT2AMEN1LMNAALDH1A1CA12 | |
| SCHEMBL22204406 | 0.74 | MEN1 (0.63) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL699184 | 0.74 | KEAP1 (0.88) | KMT2AL3MBTL1CA12CA9KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57016876-A | — | — | None | — | — | JP | disclosed |
| EP-0549796-B1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEM IND INC (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5391552-A | Has strong antagonism against calcium with less side effects | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0612738-A1 | Diphenylpiperazine derivative and drug for circulatory organ containing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0549796-A1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES INC (JP) | 1993-07-07 | — | — | EP | disclosed |
| JP-S5716876-A | MONOEPOXIDE | TEIJIN LTD | 1982-01-28 | — | — | JP | disclosed |