Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PER2 | O15055 | 2/20 | 0.43 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899900 | 0.82 | L3MBTL1 (0.61) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL8613559 | 0.79 | KMT2A (0.86) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL8485460 | 0.74 | CA2 (0.50) | LMNAALDH1A1L3MBTL1POLBKDM4E | |
| SCHEMBL1030304 | 0.73 | LMNA (0.51) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL2966811 | 0.72 | LMNA (0.73) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL1618178 | 0.72 | LMNA (0.73) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL36896 | 0.72 | LMNA (0.54) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL4554082 | 0.72 | TSHR (0.56) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL9866782 | 0.72 | ALDH1A1 (0.54) | LMNAALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL8490028 | 0.72 | PER2 (0.49) | LMNAALDH1A1L3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549796-B1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEM IND INC (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5391552-A | Has strong antagonism against calcium with less side effects | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0612738-A1 | Diphenylpiperazine derivative and drug for circulatory organ containing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0549796-A1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES INC (JP) | 1993-07-07 | — | — | EP | disclosed |