Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613604 | 1.00 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9602549 | 1.00 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8618502 | 0.86 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8618505 | 0.86 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8618499 | 0.86 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11169631 | 0.81 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL968132 | 0.81 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL968131 | 0.81 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5694533 | 0.81 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8344610 | 0.81 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716948-A | 3-substituted carbacephems | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0644886-A1 | 3-SUBSTITUTED CARBACEPHEMS | PFIZER INC. (US) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025551-A1 | 3-SUBSTITUTED CARBACEPHEMS | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | disclosed |
| EP-0188254-B1 | CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4761410-A | MICROBIOCIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| EP-0188254-A2 | Cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |