Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609389 | 0.81 | ALDH1A1 (0.41) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL8612957 | 0.80 | ALDH1A1 (0.50) | KDM4ERAB9AALDH1A1TDP1MEN1 | |
| SCHEMBL8609972 | 0.72 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL8608979 | 0.69 | TSHR (0.40) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL7476480 | 0.67 | ADORA3 (0.53) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL8191455 | 0.67 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL9094909 | 0.67 | GRIA1 (0.51) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL8674575 | 0.66 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL7656452 | 0.66 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL7477922 | 0.65 | ADORA3 (0.52) | GRIA1GRIA2GRIA3GRIA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |