SCHEMBL8613816

SCHEMBL8613816

C=CC(=O)OCCC(C)(C)OOC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 4/20 0.47
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
CYP3A4 P08684 2/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.44
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8614980 0.88 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27498047 0.84 ATM (0.31)
SCHEMBL8965587 0.81 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9241209 0.81 ALDH1A1 (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3368716 0.81 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9245659 0.80 THRB (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL108963 0.80 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1015244 0.79 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8966168 0.79 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2741578 0.79 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3559153-B1 EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS ARKEMA INC (US) 2025-07-30 EP disclosed
US-11203672-B2 Efficient curative for free radically-crosslinkable polymers ARKEMA INC. (US) 2021-12-21 US disclosed
US-20190338086-A1 EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS ARKEMA INC. 2019-11-07 US disclosed
EP-3559153-A1 EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS Arkema, Inc. (US) 2019-10-30 EP disclosed
EP-3548969-A1 INITIATOR BLENDS AND PHOTOCURABLE COMPOSITIONS CONTAINING SUCH INITIATOR BLENDS USEFUL FOR 3D PRINTING Arkema, Inc. (US) 2019-10-09 EP disclosed
WO-2018118641-A1 EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS ARKEMA INC. (US) 2018-06-28 WO disclosed
EP-0667339-B1 Novel unsaturated peroxides, polymeric peroxides derived therefrom and their uses ATOCHEM NORTH AMERICA ELF (US) 1998-05-06 EP disclosed
US-5494988-A FREE RADICAL INITIATORS AS MONOMERS; CROSSLINKING UNSATURATED POLYESTERS; ADDITION, GRAFT AND BLOCK POLYMERIZATION; COMPATIBILIZING BLENDS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-02-27 US disclosed
US-5489699-A USED AS FREE RADICAL GENERATOR, POLYMERIZING ETHYNICALLY UNSATURATED MONOMERS, CURING AGENT, RHEOLOGICAL MODIFIER,AND FOR GRAFTING AND COMPATIBILIZING POLYMER BLEND ELFATOCHEM NORTH AMERICA, INC. (US) 1996-02-06 US disclosed
US-5475072-A Curing; crosslinking; modifiying; grafting; compatibilizing ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-12 US disclosed
EP-0667339-A1 Novel unsaturated peroxides, polymeric derived therefrom and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-08-16 EP disclosed