Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HGFAC | Q04756 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517678 | 0.85 | VCP (0.55) | HGFACTTRMAPTKMT2AMEN1 | |
| SCHEMBL28982636 | 0.81 | ALOX5 (0.57) | HGFACTTRMAPTKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL27995845 | 0.80 | CES2 (0.58) | HGFACTTRMAPTKMT2AMEN1 | |
| SCHEMBL70054 | 0.80 | ALOX5 (0.58) | HGFACTTRMAPTKMT2AMEN1 | |
| SCHEMBL8612255 | 0.80 | KMT2A (0.67) | HGFACMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL20591969 | 0.80 | HGFAC (0.50) | HGFACTTRMAPTKMT2AMEN1 | |
| SCHEMBL20591991 | 0.80 | HGFAC (0.50) | HGFACTTRMAPTKMT2AMEN1 | |
| SCHEMBL5981327 | 0.79 | MAPT (0.68) | TTRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL19320489 | 0.79 | HGFAC (0.51) | HGFACTTRMAPTKMT2AMEN1 | |
| SCHEMBL20591948 | 0.79 | KMT2A (0.53) | HGFACTTRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5851546-A | Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1998-12-22 | — | — | US | disclosed |