Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.79 |
| ▸ | CA2 | P00918 | 1/20 | 0.79 |
| ▸ | PLK1 | P53350 | 1/20 | 0.79 |
| ▸ | CA9 | Q16790 | 1/20 | 0.79 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.73 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086559 | 0.88 | CA1 (0.75) | CA1CA2PLK1CA9EPHX1 | |
| SCHEMBL18606712 | 0.88 | CA1 (1.00) | CA1CA2PLK1CA9EPHX1 | |
| SCHEMBL13454582 | 0.88 | CA1 (0.75) | CA1CA2PLK1CA9EPHX1 | |
| SCHEMBL17066704 | 0.86 | GPR55 (0.86) | CA1CA2PLK1CA9EPHX1 | |
| N-(Phenylcarbamothioyl)Benzamide SCHEMBL2341910 | 0.85 | EPHX1 (1.00) | CA1CA2PLK1CA9EPHX1 | |
| SCHEMBL8616503 | 0.84 | EPHX1 (0.83) | CA1CA2PLK1CA9EPHX1 | |
| SCHEMBL31321777 | 0.83 | ALDH1A1 (0.85) | CA1CA2PLK1CA9EPHX1 | |
| SCHEMBL27451748 | 0.83 | MIF (0.83) | CA1CA2PLK1CA9EPHX1 | |
| SCHEMBL8614312 | 0.82 | PTPN7 (0.74) | PRMT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13454566 | 0.82 | MAPT (1.00) | CA1CA2PLK1CA9EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| EP-0611754-B1 | Dimerized thiourea derivatives, near-infrared absorbents comprising the same, and heat wave shielding materials comprising the same | JUJO PAPER CO LTD (JP) | 1998-04-22 | — | — | EP | disclosed |
| US-5723075-A | HEAT RESISTANT ABSORBERS WITH RESINS FOR SHIELDS | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0611754-A1 | Dimerized thiourea derivatives, near-infrared absorbents comprising the same, and heat wave shielding materials comprising the same | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | CA1 4355/4885CA2 3158/4885PLK1 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.