Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520545 | 0.85 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL375765 | 0.80 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| Methyl Alcohol SCHEMBL3396777 | 0.79 | ALDH1A1 (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL78000 | 0.77 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6013805 | 0.77 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL29390571 | 0.77 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL28866513 | 0.77 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7500894 | 0.76 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| Water SCHEMBL7798110 | 0.76 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL15662173 | 0.75 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705630-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0566162-B1 | 2'-Methylidenepyrimidine Nucleoside Compounds, their use and method for production thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0310673-B1 | 2'-ALKYLIDENEPYRIMIDINE NUCLEOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | YAMASA SHOYU KK (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-5430139-A | Viricides; effective against herpes and cytomegalo viruses | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5401726-A | Antitumor agent | YOSHITOMI PHARACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0360018-B1 | 2'-Methylidenepyrimidin nucleoside compounds, their use and method for production thereof. | YOSHITOMI PHARMACEUTICAL (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5300636-A | 2'-alkylidenepyrimidine nucleoside compounds and a process for production of same | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0566162-A1 | 2'-Methylidenepyrimidine Nucleoside Compounds, their use and method for production thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5047520-A | Viricides, dna virus of herpes virus family | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0310673-A1 | 2'-ALKYLIDENEPYRIMIDINE NUCLEOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1989-04-12 | — | — | EP | disclosed |