Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614140 | 0.96 | LMNA (0.42) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL28302095 | 0.96 | LMNA (0.39) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL8617013 | 0.92 | LMNA (0.33) | LMNATHRB | |
| SCHEMBL11801785 | 0.89 | LMNA (0.42) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL28219341 | 0.89 | LMNA (0.42) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL28300998 | 0.88 | THRB (0.32) | LMNATHRB | |
| SCHEMBL8618007 | 0.86 | LMNA (0.40) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL8617322 | 0.86 | LMNA (0.40) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL8612835 | 0.86 | LMNA (0.40) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL8612589 | 0.85 | THRB (0.30) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837085-A1 | POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-04-22 | — | — | EP | disclosed |