SCHEMBL8617013

SCHEMBL8617013

OC(F)(C(O)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8612589 0.92 THRB (0.30) LMNATHRB
SCHEMBL8614923 0.92 LMNA (0.37) LMNATHRB
SCHEMBL8614140 0.89 LMNA (0.42) LMNATHRB
SCHEMBL28302095 0.87 LMNA (0.39) LMNATHRB
SCHEMBL28300998 0.87 THRB (0.32) LMNATHRB
SCHEMBL4658353 0.87 THRB (0.32) LMNATHRB
SCHEMBL8618195 0.84 THRB (0.30) LMNATHRB
SCHEMBL11801785 0.81 LMNA (0.42) LMNATHRB
SCHEMBL28219341 0.81 LMNA (0.42) LMNATHRB
SCHEMBL8618007 0.78 LMNA (0.40) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed