Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064961 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KMT2AGAAGRNSORT1 | |
| SCHEMBL10568581 | 0.83 | KDM4E (0.51) | ALDH1A1KMT2AGAARPA1POLB | |
| SCHEMBL28644955 | 0.82 | HPGD (0.50) | ALDH1A1KMT2AGAARPA1POLB | |
| SCHEMBL7268 | 0.79 | KMT2A (0.68) | ALDH1A1KMT2AGAAPOLBMAPT | |
| SCHEMBL28625965 | 0.78 | KMT2A (0.67) | ALDH1A1KMT2AGAAPOLBMAPT | |
| SCHEMBL1143854 | 0.77 | RPA1 (0.67) | ALDH1A1KMT2ARPA1MEN1SMN1; SMN2 | |
| SCHEMBL25078568 | 0.72 | P2RY1 (0.46) | ALDH1A1KMT2AGAAPOLBMAPT | |
| SCHEMBL18694403 | 0.72 | KMT2A (0.55) | ALDH1A1KMT2AGAAPOLBMAPT | |
| SCHEMBL15636600 | 0.71 | CNR1 (0.61) | ALDH1A1KMT2ACNR1CNR2MEN1 | |
| SCHEMBL18693864 | 0.71 | ALDH1A1 (0.56) | ALDH1A1GAARPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750550-A | RESPIRATORY SYSTEM DISORDERS | SANOFI (FR) | 1998-05-12 | — | — | US | disclosed |