Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615684 | 0.92 | ESR1 (0.43) | TACR3ACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8620932 | 0.89 | POLB (0.51) | TACR3ACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8617753 | 0.89 | ACP1 (0.51) | ACP1ABCB1ABCC1ABCG2MEN1 | |
| SCHEMBL8614861 | 0.87 | AKR1C3 (0.53) | ACP1ABCB1ABCC1ABCG2MEN1 | |
| SCHEMBL8618234 | 0.87 | RXFP1 (0.44) | TACR3ACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8617739 | 0.87 | ALDH1A1 (0.47) | TACR3ACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8619389 | 0.87 | TACR3 (0.41) | TACR3ACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8615938 | 0.87 | TACR3 (0.41) | TACR3ACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8614932 | 0.86 | ELANE (0.50) | TACR3ACP1MEN1KMT2A | |
| SCHEMBL8620107 | 0.84 | HTT (0.37) | TACR3ACP1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |