Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752192 | 0.82 | HTR7 (0.42) | NOS3NOS1HRH3ALDH1A1HTR7 | |
| SCHEMBL8612335 | 0.82 | HTR7 (0.44) | HRH3KDM4EALDH1A1HTR7SMN1; SMN2 | |
| SCHEMBL7756067 | 0.82 | MAPT (0.40) | HRH3KDM4EALDH1A1HTR7DRD2 | |
| SCHEMBL8621045 | 0.82 | HRH3 (0.37) | HRH3KDM4EHTR7DRD2DRD1 | |
| SCHEMBL7094760 | 0.77 | HRH3 (0.52) | HRH3KDM4EALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL8389373 | 0.75 | HTR7 (0.40) | NOS3NOS1HRH3KDM4EALDH1A1 | |
| SCHEMBL9072587 | 0.74 | SMN1; SMN2 (0.45) | KDM4EALDH1A1DRD2DRD4SMN1; SMN2 | |
| SCHEMBL7756672 | 0.74 | HRH3 (0.38) | HRH3KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15880025 | 0.73 | HRH3 (0.58) | HRH3KDM4EALDH1A1PARP1 | |
| SCHEMBL9098005 | 0.72 | NR4A2 (0.51) | HRH3KDM4EHTR7HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |