Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615555 | 0.88 | DGAT1 (0.56) | MCL1MAOBDGAT1NPC1RAB9A | |
| SCHEMBL2636350 | 0.80 | ALOX5 (0.73) | ALOX5MAOBCYP3A4NPC1RAB9A | |
| SCHEMBL29576561 | 0.80 | ALOX5 (0.73) | ALOX5MAOBCYP3A4NPC1RAB9A | |
| SCHEMBL27865448 | 0.80 | CYP2A6 (0.50) | NPC1RAB9AGSTP1MEN1KMT2A | |
| SCHEMBL8617394 | 0.80 | ALOX5 (0.59) | ALOX5MCL1MAOBCYP3A4NPC1 | |
| SCHEMBL8613941 | 0.80 | ALOX5 (0.59) | ALOX5MCL1MAOBCYP3A4NPC1 | |
| SCHEMBL8612974 | 0.78 | MAOB (0.48) | ALOX5MCL1MAOBCYP3A4MAOA | |
| SCHEMBL387683 | 0.78 | ERN1 (0.44) | MCL1RAB9AXDHSMN1; SMN2 | |
| SCHEMBL8641406 | 0.77 | MAOB (0.57) | ALOX5MCL1MAOBRAB9AGSTP1 | |
| SCHEMBL12470770 | 0.75 | ALOX5 (0.57) | ALOX5MAOBCYP3A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |
| EP-0517498-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |