Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.46 |
| ▸ | HRAS | P01112 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704841 | 0.80 | MMP9 (0.58) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL2030203 | 0.80 | PPARG (0.67) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL8760872 | 0.80 | PPARG (0.67) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL2035189 | 0.80 | PPARG (0.67) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL6892246 | 0.79 | MAOB (0.44) | MMP9MMP8PPARGLTA4HHRAS | |
| SCHEMBL684726 | 0.79 | PPARG (0.62) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL13013217 | 0.79 | PPARG (0.62) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL13227760 | 0.79 | PPARG (0.62) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL23901567 | 0.78 | LTA4H (0.61) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL3499760 | 0.78 | LTA4H (0.65) | MMP9MMP8PPARGMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046625-A1 | DIPEPTIDE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |