Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941438 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TP53HPGDTSHRMAPK1 | |
| SCHEMBL8764047 | 0.78 | TSHR (0.36) | ALDH1A1TP53HPGDTSHRMAPK1 | |
| Benzyl Thiocyanate SCHEMBL27730692 | 0.78 | MAOB (0.48) | ALDH1A1HPGDTSHRHSD17B10MAOA | |
| Benzyl Thiocyanate SCHEMBL129196 | 0.78 | MAOB (0.48) | ALDH1A1HPGDTSHRHSD17B10MAOA | |
| Benzyl Thiocyanate SCHEMBL11858619 | 0.76 | MAOB (0.47) | ALDH1A1HPGDTSHRHSD17B10MAOA | |
| SCHEMBL28710323 | 0.74 | MAOA (0.52) | ALDH1A1TP53SMN1; SMN2MAOAMAOB | |
| SCHEMBL14396518 | 0.74 | CYP2A6 (0.52) | ALDH1A1TP53HPGDHSD17B10MAOA | |
| SCHEMBL4921123 | 0.74 | MAOA (0.52) | ALDH1A1MAPK1MAOAMAOBIDO1 | |
| SCHEMBL13001469 | 0.74 | ESR1 (0.44) | ALDH1A1TDP1IDO1 | |
| SCHEMBL28637924 | 0.74 | MAOB (0.52) | ALDH1A1HPGDSMN1; SMN2HSD17B10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835242-A1 | THIOAMIDES S-OXIDES FOR USE AS PESTICIDES | Novartis AG (CH) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997000859-A1 | THIOAMIDES S-OXIDES FOR USE AS PESTICIDES | NOVARTIS AG (CH) | 1997-01-09 | — | — | WO | disclosed |