SCHEMBL8615693

SCHEMBL8615693

Cc1cc(N(C)C)ccc1-c1cc(-c2ccccc2)nc(-c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 2/20 0.49
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
TLR9 Q9NR96 1/20 0.44
ADK P55263 1/20 0.44
PKM P14618 2/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.42
ADORA2A P29274 2/20 0.41
ESR2 Q92731 2/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA1 P30542 1/20 0.41
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16491626 0.85 ESR2 (0.55) PSMB5MEN1KMT2AADKRAB9A
SCHEMBL8621443 0.81 PSMB5 (0.43) PSMB5MEN1KMT2ATLR9ADK
SCHEMBL4353469 0.78 LTB4R (0.55) MEN1KMT2ATLR9ADKRAB9A
SCHEMBL8621730 0.78 LTB4R (0.55) MEN1KMT2ATLR9ADKRAB9A
SCHEMBL8616881 0.78 LTB4R (0.55) MEN1KMT2ATLR9ADKRAB9A
SCHEMBL13203329 0.78 MEN1 (0.52) MEN1KMT2APKMRAB9ANPC1
SCHEMBL28196231 0.78 ENPP3 (0.54) MEN1KMT2APKMRAB9ANPC1
SCHEMBL21277258 0.78 ALDH1A1 (0.45) MEN1KMT2APKMRAB9ANPC1
SCHEMBL28588008 0.78 MAPT (0.48) MEN1KMT2APKMRAB9ASMN1; SMN2
SCHEMBL18910859 0.77 MEN1 (0.58) PSMB5MEN1KMT2ATLR9ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4262078-A SUBLIMABLE COLOR-FORMING PYRIDINE DERIVATIVE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-04-14 US claimed
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
US-4262078-A SUBLIMABLE COLOR-FORMING PYRIDINE DERIVATIVE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-04-14 US disclosed