Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617465 | 0.84 | TBXA2R (0.46) | AKR1B1TBXA2RTBXAS1 | |
| SCHEMBL8617506 | 0.84 | TBXA2R (0.46) | AKR1B1TBXA2RHTR2AHTR2CTBXAS1 | |
| SCHEMBL11836856 | 0.82 | CYP1A2 (0.46) | TBXA2RHTR2AHTR2CHRH1 | |
| SCHEMBL9331557 | 0.81 | HTR2A (0.43) | TBXA2RHTR2AHTR2CHRH1 | |
| SCHEMBL8614670 | 0.81 | TBXA2R (0.47) | TBXA2RHTR2ATBXAS1 | |
| SCHEMBL22049559 | 0.81 | HTR2A (0.42) | TBXA2RHTR2AHTR2CHRH1 | |
| SCHEMBL1389876 | 0.81 | HTR2A (0.55) | EGFRHTR2AHTR2CHRH1 | |
| SCHEMBL5338882 | 0.81 | LMNA (0.52) | EGFR | |
| SCHEMBL14407922 | 0.81 | HTR2A (0.55) | EGFRHTR2AHTR2CHRH1 | |
| Hydrochloric Acid SCHEMBL10743675 | 0.80 | HTR2A (0.53) | EGFRHTR2AHTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588608-B1 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-4816591-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4816591-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4816591-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4585788-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4585788-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4585788-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4576960-A | 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives | HOECHST ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-03-18 | — | — | US | disclosed |
| US-4345087-A | Process for preparing heteroarylbenzoxepin-acetic acids, precursors and derivatives thereof | AMERICAN HOECHST CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4124713-A | Oxopyridobenzoxepin-acetic acids and derivatives thereof useful as antiinflammatory and analgesic agents | AMERICAN HOECHST CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4117152-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOECHST CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4107177-A | CYCLIZING (CARBOXYTHIENYLOXY)BENZENEACETIC ACID WITH DEHYDRATING AGENT | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107321-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107322-A | Benzyl and related esters of 6,11-dihydrodibenz[b,e]oxepin-acetic acids | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107322-A | Benzyl and related esters of 6,11-dihydrodibenz[b,e]oxepin-acetic acids | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4101559-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4081457-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4025640-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3944566-A | CARDIOVASCULAR | BOEHRINGER MANNHEIM GMBH (DT) | 1976-03-16 | — | — | US | disclosed |