Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615765 | 0.84 | AKR1B1 (0.45) | TBXA2RAKR1B1TBXAS1 | |
| SCHEMBL8617506 | 0.84 | TBXA2R (0.46) | TBXA2RAKR1B1TBXAS1 | |
| SCHEMBL8614670 | 0.84 | TBXA2R (0.47) | TBXA2RTBXAS1 | |
| SCHEMBL8797377 | 0.81 | TBXA2R (0.44) | TBXA2RKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL7509154 | 0.79 | KMT2A (0.42) | TBXA2RKMT2ATSHR | |
| SCHEMBL9556925 | 0.78 | TBXA2R (0.46) | TBXA2RKMT2ATBXAS1 | |
| SCHEMBL22193837 | 0.77 | KMT2A (0.38) | TBXA2RKMT2ATSHR | |
| SCHEMBL8797201 | 0.77 | KMT2A (0.39) | TBXA2RKMT2ATSHR | |
| SCHEMBL8620574 | 0.76 | TBXA2R (0.40) | TBXA2RAKR1B1TBXAS1 | |
| SCHEMBL10881346 | 0.76 | KMT2A (0.39) | TBXA2RKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588608-B1 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |